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In a 2025 review, the authors describe this species as occupying an extraordinary niche in the human gut, and a model organism studied for its ability to modulate human health and gut microbiome structure.13 In animal studies, it has slowed the development and progression of diabetes , obesity , and irritable bowel disease .14 In human trials, it has helped participants reduce their BMI and improve their diabetic markers.12 Its effects on obesity and diabetes have been recreated in humans as well
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NICE criteria include BMI 40 kg/m or 35 kg/m with comorbidities, with consideration for BMI 30-34.9 kg/m with recent-onset type 2 diabetes and lower thresholds for some ethnic groups
Relation between resting amygdalar activity and cardiovascular events: a longitudinal and cohort study
