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Combining a compound with established Phase 3 long-term safety with a compound that has zero combination-specific safety data does not produce a combined profile that can be defended as long-term safe
2 Results 2.1 Pharmacokinetic studies of BPC157 in rats The effective dose of BPC157 for the treatment of various injuries in mice, rats, and rabbits ranges from 6 to 50 g/kg ( The mean (+SD) plasma concentration of BPC157 versus time curves following administration of various BPC157 doses in rats are shown in Figures 1AC, and the corresponding pharmacokinetic parameters are presented in Tables 1Tables 3
Hence, the two chromophores are optically coupled and excitation of either can trigger AdoCbl photoconversion, thereby expanding light sensitivity to cover most of the visible spectrum
