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In the Phase 3 REDEFINE-1 trial, adding cagrilintide to semaglutide pushed average weight loss from 14.9% to 20.4%

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Established Role in Obesity Management Guidelines Semaglutide is included in major obesity management guidelines as a first-line pharmacologic option for adults with obesity or overweight and weight-related comorbidities

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Abdominal fat provides convenient systemic administration when local injection proves difficult or for diffuse ankle issues

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