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9 1

The development of these agents underscores the continuous improvement of the pharmacokinetic and pharmacodynamic profiles of these peptide agents [ Table 1 ], expanding their applications beyond T2DM and obesity to encompass cardiovascular disease event reduction [ Table 2 ]

once-weekly dosing

By excluding studies that are ranked at increased risk of bias according to quality assessments (e.g., low quality in selection or measurement), meta-analyses provided similar effect estimates