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Moreover, taurine interferes with mitochondria-dependent apoptosis and the unfolded protein response [44], it downregulates the p53-Chk1 pathway [45] and upregulates extracellular-signal-regulated kinases (ERK) and Wnt/-catenin pathway [44, 46]
A caveat when interpreting our results is that in many cases we treated cells with relatively high doses of agonist in order to establish differences in maximal response
Springer Singapore, pp 257281
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