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It is given once a week by subcutaneous injection under the skin in the abdomen, thigh or upper arm

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By phagocytosing chemically modified low-density lipoprotein (LDL), these cells become foam cells, which make up the largest part of the core of the plaque

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The lethal dose in humans would be approximately 21,000mg for a 70kg person, making the 1-3mg daily doses used in typical protocols extremely safe from a toxicity standpoint

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