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The 48 week BELIEVE Phase 2 compared a multiple placebo arm to semaglutide4 (1.0mg or 2.4mg), bimagrumab (10 mg/kg, 30 mg/kg), and sema-bima (1.0mg, 2.4mg semaglutide X 10 mg/kg, 30 mg/kg bimagrumab)
Other research investigating gastrointestinal motility has used doses near 1 mg/kg in rodent models to assess effects on gastric emptying and intestinal motility
Most cases of heartburn can be managed with dietary modifications, lifestyle changes, or acid-suppressing medications while continuing treatment
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