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doi: 10.1177/1178646920936279 46 LongoNFrigeniMPasqualiM
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Molecular mimicry The structural proximity between an exogenous antigen (for instance, viral) and an autoantigen, which may result in the induction of autoimmunity
GLP-1RA activates the GLP-1 receptor in platelets, through an cyclic adenosine monophosphate/protein kinase (AMP/PKA)-dependent mechanism to prevent systemic inflammation, vascular dysfunction, and end-organ damage, thereby significantly reducing the microvascular thrombosis induced by endotoxin blood disease and mortality (Steven et al., 2016) (Tests on human vascular endothelial cells exposed to LPS have demonstrated that GLP-1 analogs reduce vascular permeability and lower the levels of pro-inflammatory cytokines (Wonhwa et al., 2016)
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