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Signs of more severe dehydration include (9): Little to no urination, or very dark yellow or amber-colored urine Dry, shriveled-looking skin Dizziness or lightheadedness Irritability or confusion Rapid heartbeat Rapid breathing Sunken eyes Extreme tiredness or listlessness In severe cases, shock or loss of consciousness Spotting these signs early can help you take action before dehydration becomes a bigger issue, especially if youre managing side effects from GLP-1 medications

At least one well-designed study suggests that carnitine supplements may improve muscle function and exercise capacity in those with PVD

[6] The most common side effects of orforglipon noted in clinical trials were vomiting, diarrhea, nausea, upset stomach, and constipation

(PubMed) Teather LA, Wurtman RJ