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Nearly all of the evidence behind it comes from animal and in-vitro (preclinical) studies , not from completed human efficacy trials
Contact your provider promptly if you have: Persistent vomiting or inability to keep fluids down Severe or worsening abdominal pain Signs of dehydration (dizziness, very dark urine, fainting, rapid heartbeat) Severe constipation lasting multiple days with significant pain Symptoms that interfere with daily function or do not improve after supportive changes Discuss dose and timing adjustments If side effects are strong after a dose increase, your clinician may consider slowing the titration, changing supportive strategies, or reviewing nutrition and hydration
Additionally, it was shown that these NPs prevented cancer cells from expressing endothelial growth factor (VEGF), which reduced metastasis (126)
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