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Developed by Eli Lilly, it is administered as a once-weekly subcutaneous injection
For the open-label treatment extension period analysis, only the efficacy estimand was used due to the lack of a true placebo group
The connection between GLP-1 dry mouth and other side effects Dry mouth rarely exists in isolation
Indeed, eGFR values were greater in patients on tirzepatide compared to those on insulin glargine, with a mean eGFR decline rate of 1.4 ml/min/1.73 m 2 per year in tirzepatide users and a between-group difference in eGFR reduction of 2.2 ml/min/1.73 m 2 per year [49]
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