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Early changes usually appear by the fourth to sixth session, with clearer improvement in the following weeks
[1] Monitoring recommendations for patients using both medications include: Regular blood glucose testing particularly post-lunch and early evening when morning prednisolone is used Consider action if readings are persistently above 12 mmol/L (with individualisation based on your care plan) HbA1c measurement every 3 months for patients with diabetes or prediabetes Fasting glucose checks if not previously diabetic, particularly during corticosteroid therapy Symptom awareness for hyperglycaemia (increased thirst, frequent urination, fatigue, blurred vision) Patients with established diabetes may require adjustments to their glucose-lowering regimen whilst on prednisolone
FDA approves Lilly's Foundayo (orforglipron), the only GLP-1 pill for weight loss that can be taken any time of day without food or water restrictions
NICE guidance prioritises SGLT2 inhibitors for those with established or high risk of cardiovascular or kidney disease, with GLP-1 receptor agonists as add-on or alternative therapy where appropriate
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