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BPC-157 operates primarily at the local tissue level: it upregulates VEGF and EGF expression at the injury site, modulates the nitric oxide system to improve blood flow to damaged tissue, and directly promotes fibroblast migration and collagen organization through the FAK-paxillin pathway
In the body, NAD+ (nicotinamide adenine dinucleotide) plays an important role in energy production, metabolism, and DNA repair
Within seconds of the sensing of increased reactive oxygen species (ROS), several enzymes of glycolysis (particularly glyceraldehyde-3-phosphate dehydrogenase and pyruvate kinase) are inhibiting allowing for the diversion of glucose carbons into the PPP
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