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While this medication has demonstrated significant efficacy in clinical trials, it carries an FDA Boxed Warning regarding the risk of thyroid C-cell tumors, including medullary thyroid carcinoma (MTC)
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Studies comparing routes consistently show IV glutathione produces five to ten times higher peak plasma concentrations than oral dosing (PubMed PMID: 24791752)
Mutations in the CEL VNTR cause a syndrome of diabetes and pancreatic exocrine dysfunction
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