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Similarly, expression of cell signature genes, transthyretin ( TTR ), vitamin Dbinding protein ( GC ), crystallin A2 ( CRYBA2 ), aldehyde dehydrogenase 1 family member A1 ( ALDH1A1 ), and transmembrane 4 L 6 family member 4 ( TM4SF4 ), was highest in the -3 and 4 subclusters (Figure 3D)
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Continued scrutiny of drug pricing appears likely, particularly given the rapidly evolving and uncertain US drug pricing environment, adding uncertainty for the companies set to enter the GLP-1 space
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