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doi:10.1186/1472-6963-10-159 Sarwer DB, Gasoyan H, Bauerle Bass S, Spitzer JC, Soans R, Rubin DJ

Table 1 Published animal and human researches on the impact of GLP-1 on bone metabolism

MDR-001 (MindRank) MDR-001 is one of the clearest examples of the speed thesis in oral GLP-1: the company states it progressed from discovery to Phase III in ~4.5 years, with Phase IIb data showing ~10.3% mean weight reduction at Week 24 and low TEAE-related discontinuation (reported as 0.8%)