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Sustained deficits in neuronal energy metabolism have been linked to the early stages of neurodegenerative processes, including the accumulation of beta-amyloid plaques and tau protein tangles, both hallmarks of Alzheimer's disease pathology [2]
Their primary purpose is metabolic health, and they should not be used as a substitute for specialized reproductive care
This was linked to improved bone mineral density in the tested animals [18]
We and others have shown that circulating leptin levels are reduced in chronic stress animal models of depression [15,16,17], whereas systemic and intracerebroventricular injections of leptin produce antidepressant-like behavioral effects [15, 18,19,20]
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