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GLP-1 agonists (like semaglutide) and dual GLP-1/GIP agonists (like tirzepatide) work by mimicking natural hormones that regulate your appetite and digestion

In addition, the basal GLP-1 secretion was significantly inhibited by 1-M pasireotide treatment in GLUTag cells, and the inhibitory effect of pasireotide was reversed by PTX treatment (Fig

Type-I IFN: Type-I IFN facilitates dendritic cell (DC) maturation, enhances autoimmune T cell survival, and activates autoantibody-producing B cells, primarily through sustained IFN- production, autophosphorylation, and activation of the IFN- receptor (IFNAR)-associated Janus kinases (JAKs) and signal transducers and activators of transcription (STATs) (87, 88)