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Although meta-analysis (97 comparisons across 95 trials) demonstrated a statistically significant but clinically unimportant increase in FPG [fasting plasma glucose] (Hall et al., 2020), the impact of any diuretic on glucose homeostasis seems to depend on several factors, including the type of diuretic used and the specific metabolic context on which these diuretics are being studied (Grossman et al., 2011)
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However, current guidelines do not recommend L-carnitine for cancer-related fatigue (Bower 2024, S3-Leitlinie) and advise against its use for preventing chemotherapy-induced peripheral neuropathy (Loprinzi 2020, Lyman 2018)
arXiv preprint arXiv:1810.04805
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