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An association of treatment with GLP-1RA receptor agonists and DR was originally reported in the SUSTAIN-6 trial, which demonstrated a statistically significant increase in risk of new or worsening DR, with 3% incidence in the semaglutide group versus 1.8% in the placebo group (hazard ratio, 1.76
FDA Approval of GLP-1 and dual GIP/GLP-1 Drugs If You Have Type 2 Diabetes GLP-1 and dual GIP/GLP-1 medications are FDA-approved adjuncts for type 2 diabetic patients
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