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The GLP-1 onset timeline rewards patience, which is the opposite of what most people expect from a weight loss medication

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According to one analysis of clinical trials, L-carnitine may reduce weight by about 1.3 kg and decrease body mass index by about 0.5 kg/m2 compared to control in both nonobese and obese adults [28]

Trial participants showed better blood sugar control and lower blood pressure on retatrutide, which is unsurprising given its mechanism (more insulin, less appetite, etc.)