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Remember that decisions about GLP-1 therapy should be made collaboratively, considering your individual circumstances, preferences, and the latest available evidence
Administration of GLP-1 RAs via the subcutaneous route poses several drawbacks including invasiveness, patient discomfort, systemic side effects, and the need to penetrate the restrictive bloodbrain barrier (BBB)
In particular, hemocompatibility of blood-contacting devices is tested in vitro in accordance with the ISO standard 10993-4 guidelines, and this testing comprises evaluation of thrombosis, the blood coagulation system, the complement system, and multiple effects on platelets and leukocytes [464]
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