The supplements usually contain herbal ingredients like berberine, yerba mate, green tea, coffee, prebiotics, probiotics, turmeric, ginseng and other herbal extracts that may slightly boost the bodys natural GLP-1, White notes
If genuine tachyphylaxis is confirmed, strategies include dose escalation to the next tier, brief treatment breaks of 2 to 4 weeks to allow receptor resensitization, or switching to alternative GLP-1 agonists like semaglutide to provide different receptor activation patterns
Statistical significance was determined using two-tailed Students t test through GraphPad Prism5 software unless otherwise mentioned
Overall, micro dosing is very unique and customizable compared to standard dosing