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Orthologs of the genes encoding the ligands ( GCG, GIP ), their receptors ( GLP-1R, GIPR ) and DPP-4 have been identified in a range of vertebrate species (reviewed in refs 8, 9, 10)
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Novo Nordisk conducted a randomized, double-blind, placebo-controlled phase 2b clinical trial called ELAD to evaluate the neuroprotective effects of liraglutide in patients with mild AD (Femminella et al., 2019)
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