Your body actually produces it on its own, mostly in the liver, and it plays a key role in protecting your cells from damage
2.3 Neuroinflammation Some studies have shown that berberine activates macrophages and increases their phagocytic function, increases the production of interleukin (IL)-1, and enhances non-specific immunity, can be used as a neuroprotective agent to prevent Alzheimers disease (Kumazawa et al., 1984
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Regulatory factors from NAM, ATAF1/2, and CUC2 and WRKYGQK in its DNA-binding domain (WRKY, NAC) have been identified to play the co-regulation of metal induced gene expression and thereby assist genomic stability