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Statin therapy was found to be associated with significantly improved survival free from urgent transplantation (84% in statin-treated and 70% in non-treated patients) in statin treated group comprising of patients with higher rates of hypertension, diabetes, and smoking in comparison to controls (left ventricular ejection fraction and cholesterol levels were similar between treated and non-treated patient groups) [96]

Side effects may decrease (because the effective dose is lower), giving a false impression that tolerance has developed

Therefore, mitochondria imbalance has been associated with multiple neurodegenerative diseases, such as AD, Parkinson and MS, among others (Area-gomez et al., 2018

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