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The rare individual who might consider this combination needs exceptional GI tolerance proven on prior GLP-1s, physician supervision with frequent monitoring, ability to afford $15,000-30,000 annually, understanding they're experimenting on themselves, and willingness to stop immediately if severe side effects emerge
Most clients describe minimal discomfort, often less than they expected
Glitazones, the major PPAR-agonist, decreases glucose but not TGs
doi: 10.1002/j.1939-4640.1996.tb01830.x 112 AgarwalACannarellaRSalehRHarrazAMKandilHSalvioGet al
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