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In addition, impaired GPx4 expression in peripheral blood monocytes was shown to be a biomarker of increased risk of breast cancer [111]

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Complex I Complex I, most commonly called NADH dehydrogenase (also known as NADH:CoQ oxidoreductase or NADH-ubiquinone oxidoreductase), is composed of NADH dehydrogenase with FMN as cofactor, plus non-heme iron proteins having at least one iron sulfur (Fe-S) center