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The PFVYLI-CAND peptide, which includes a hydrophobic CPP sequence, showed no efficacy in inducing cell death in either cell type (Figure

3cg are the simple linear regression lines (Extended Data Table 2)

Animal-model research has examined its association with increased lipolysis and reduced body-weight gain in obese rodent models, with reported observations that these effects occurred without measurable changes to IGF-1 levels or insulin sensitivity

This leads to the secretion of IFN- and an upregulation of NKG2D ligands in the hair follicle, which can expose hair follicle-associated autoantigens and trigger an autoimmune response in alopecia areata