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In agreement with observed resistance in KO mice, levels of phosphorylated AMPK subunit (at Thr172 residue) were higher in the livers of KO mice than in WT mice in all diet groups (Fig
Findings from another study in which grape seed proanthocyanidins suppressed doxorubicin-related cardiotoxicity in rats indicated that the cardioprotective effects were mediated through antioxidant, anti-inflammatory, and antiapoptotic mechanisms (Boghdady 2013)
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