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Researchers should define the main question before selecting a model: whether the study is testing cytoprotection, migration, proliferation-associated endpoints, angiogenesis, extracellular matrix remodeling, endothelial signaling, or tissue-level recovery
Hence, it is a good practice to take lot of fluids such as water or juices
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Users often see early changes such as improved smoothness and brightness before more visible tone refinement appears
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