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In multiple animal and in-vitro studies, both peptides have demonstrated high tolerability and absence of systemic toxicity
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Regulatory agencies increasingly recognize the unique properties of peptide drugs and have developed specialized expertise in evaluating these products
In particular, GSTP1-1 is able to protect the tumor cells from apoptosis signals by inhibiting c-Jun N-terminal kinase (JNK)a member of the MAPK pathwaynon-catalytically, by direct proteinprotein association 25,26
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