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Physical Triggers and Temperature Changes Some people develop hives in response to physical stimuli: dermographism (hives that appear where skin is scratched), cold urticaria (triggered by cold air or water), pressure urticaria (triggered by tight clothing or belts), and exercise-induced hives
So the whole protocol ends up being an hour long
Research Note: In a gene-array analysis of skin cells reviewed by Pickart and Margolina in the International Journal of Molecular Sciences (2018), GHK produced a change of 50% or greater in expression for 31.2% of the human genes tested, with about 59% of those genes upregulated and 41% suppressed (Pickart & Margolina, 2018)
No topical ingredient, regardless of mechanism, can accelerate that rate
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