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Inspection of the trajectory of weight loss with time showed that weight loss with retatrutide was evident after 4-8 weeks and progressed with no evidence of plateau to the end of follow-up at 48 weeks [3]
Studies show that typically about 50% to 70% of the fat survives and integrates into the new tissue
Discuss a clear plan for GLP-1 dose adjustments or temporary holds if intolerable gastrointestinal symptoms develop
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