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At 5:00 pm, mice were administered with the vehicle (saline), semaglutide (0.5 mg/kg, s.c.), tirzepatide (0.05 mg/kg, s.c.), and retatrutide (0.05 mg/kg, s.c.)
Subsequently, blood samples were collected, and glucose levels were measured at predetermined time points (0.25, 0.5, 1, 1.5, 2, 2.5, 3, 3.5, 4, and 5 h) after glucose injection
HTN: hypertension
Phase 3 trials are currently ongoing and will provide data on longer treatment durations, maintenance protocols, and discontinuation outcomes specific to retatrutide
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