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Klesney-Tait, J., Turnbull, I
Certainly, an increase in IGF-1 action is associated with greater risk for neoplastic disease, a link further supported by this study and others targeting IGF-1Rs, but IGF-1 has been paradoxically associated with protection against osteoporosis, type 2 diabetes, cerebrovascular and cognitive decline in pre-clinical studies, as well as in some human epidemiologic studies 12
Switching between GLP-1RA medications should be viewed as a normal part of long-term obesity care, said senior author Sarah Messiah, Ph.D., M.P.H., Professor of Epidemiology and Pediatrics, Associate Dean for Research in the ODonnell School of Public Health, and Director of the Child and Adolescent Population Health Program
That space is drawing interest from companies trying to recreate parts of GLP-1 biology with biomimetic GLP-1 supplements designed to fit within dietary-supplement rules rather than drug frameworks
