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These results suggest that reduced malate and isocitrate availability likely renders shGDH1 cells unable to produce sufficient cytosolic NADPH under glucose starvation
To provide protection against oxidative stress, cells have a well-developed antioxidant system that contains low- and high-molecular compounds that can inhibit the initiation of ROS formation, "intercept" free radicals (ROS scavengers), or neutralize the formation of lipid free radicals and lipid peroxides [20]
PMID: 41327798 Eur J Pharmacol Involvement of glucagon-like peptide-1 receptor in fisetin tetramethyl ether-enhanced insulin secretion in MIN6 cells
In the presence of BSO the accumulation of a small capsid precusor (pentamer) is reduced and consequently no mature viruses are produced in virus-infected cells
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