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Combining supportive injections with GLP-1 medications is common in medical spa settings, but the decision belongs to a provider who has reviewed the full picture

Following administration of a combined oral contraceptive (0.035 mg ethinyl estradiol and 0.25 mg norgestimate) in the presence of a single dose of tirzepatide 5 mg, mean Cmax of ethinyl estradiol, norgestimate, and norelgestromin was reduced by 59%, 66%, and 55%, while mean AUC was reduced by 20%, 21%, and 23%, respectively

The death of these fibroblasts releases pro-inflammatory cytokines like IL-1 and IL-6, which recruit and activate macrophages and T cells