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The weight tends to come back because: When weight returns, your blood pressure and cholesterol levels increase, too, which raises your risk for cardiovascular disease and other complications

At the same time, since DNA synthetic-sensitive tests for anemia and erythrocyte size are routinely done in even simple medical test clinics (so that these folate mediated-biochemical effects are more often directly detected), the MTR dependent effects of B12 deficiency are becoming apparent not as anemia (as they were classically), but now mainly as an elevation of homocysteine in the blood and urine (homocysteinuria)

They are generally well tolerated when used as directed under medical supervision, but consumers should understand what to expect

Several problems can lead to a vitamin B12 or folate deficiency