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The first cohort comprised individuals who started and continued either a GLP-1 receptor agonist or DPP-4 inhibitor for the first time between January 1, 2007, and December 31, 2020
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As leukotriene LTA 4 is the precursor of all other leukotrienes as well as being a direct precursor of lipoxins, it has been suggested that as inflammation advances and LTA 4 levels rise, it starts feeding lipoxin synthesis with subsequent initiation of resolution
Rare complications include radiation-related injury to nearby neural structures, although this is uncommon with modern planning
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