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GLP-1 medications work by: Slowing gastric emptying, which keeps you feeling full for longer Increasing insulin production from the pancreas and increasing insulin sensitivity in various tissues in the body Reducing appetite by acting on hunger centers in the brain Suppressing glucagon, a hormone that raises blood sugar To support informed decision-making, its also worth distinguishing between the current FDA-approved uses of GLP-1 meds and off-label applications

The SURMOUNT and SURPASS trials put this head to head

This issue echoes healthcare providers challenges in resource-limited settings, particularly in allocating scarce treatments that require long-term sequential treatments

In the EU, patients and clinicians generally report to national competent authorities