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Timing matters enormously: Estradiol varies dramatically across the menstrual cycle

From their meta-analysis study, Ni and Du 32 showed that there is a dose-response relationship between folate and the risk of esophageal cancer (EC)

Whether GLP-1RAs exert direct modulation of the hypothalamic-pituitary-ovarian (HPO) axis beyond these metabolic pathways remains to be verified by clinical mechanistic evidence