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The risk of nutritional deficiencies may be amplified by further appetite suppression and reduced food intake
[9] [10] Additional mechanisms suggested by preclinical research include: Improved insulin receptor expression , potentially making cells more responsive to insulin Modulation of gut microbiota , which may influence metabolic health and inflammation [13] Reduction in intestinal glucose absorption , slowing the rise in blood sugar after meals Antioxidant and anti-inflammatory effects , which may theoretically protect pancreatic beta cells Whilst these mechanisms are biologically plausible, it is important to note that berberine is classified as a food supplement in the UK, not a licensed medicine
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