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Dietary strategies that complement semaglutide's mechanism include consuming smaller, more frequent meals to accommodate delayed gastric emptying and reduced stomach capacity

Jelinek J, Rafferty JA, Cmejla R, Hildinger M, Chinnasamy D, Lashford LS et al

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For example, in a thioacetamide-induced mouse model, semaglutide reduced biochemical and histological markers of liver injury, attenuated -SMA expression, decreased oxidative stress, and downregulated the canonical TGF-/Smad signalling pathway while upregulating SIRT1 and phosphorylated AMPK