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Altogether, NRF2 is a transcriptional factor of GCLC, and ACTL6A co-works with NRF2 and affects NRF2 binding to the promoter of GCLC, thereby regulates GCLC expression at the transcriptional level

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The laboratory approached BOC Sciences because of our portfolio of cationic lipid technologies and our experience with "Ethosomes" (ethanol-containing vesicles) which are known for enhancing deep skin penetration