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Studies from the US Food and Drug Administration (FDA) have found a disproportionate reporting of suicidal ideation and depression/suicidal thoughts with semaglutide and liraglutide, but not for suicidal behaviour, suicide attempts and completed suicide [27,28,29,30]
We show that GLP-1(2836) entered mouse caSMCs and ECs by macropinocytosis and activated sAC, as evidenced by the increased production of cAMP in caSMCs from WT but not sAC / mice
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