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Some individuals may achieve sufficient lifestyle modification to maintain weight loss without medication, while others may experience weight regain upon discontinuation, necessitating resumed or lifelong therapy

That means a supplement patch can be sold without proving it works the company only needs to ensure the product is safe and not adulterated

Tirzepatide (Zepbound) injection is approved for adults with obesity (BMI of 30 kg/m or higher) or overweight (BMI of 27 kg/m or higher) with at least one weight-related condition to use in addition to a reduced-calorie diet and increased physical activity

This explains why the plunger feels stuck or the needle appears cloggedthe medication itself has become unusable