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As may be expected, weekly administration of semaglutide has been associated with improvement of liver steatosis based on US assessment (Volpe et al., 2022)
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It reversed glucose dysregulation without detrimental effects on metabolically healthy animals and reduced body weight, lowered fasting blood glucose, decreased glycosylated hemoglobin (HbA1C), improved glucose tolerance, and protected pancreatic islet architecture in diabetic fatty Zucker rats 22,23,24
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