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For instance, as an increase in drug lipophilicity resulted in a proportionally higher BBB permeation rate, many drug delivery strategies were focused on an increase in lipophilicity of the CNS drugs (25)

DOI: 10.1111/dom.15306 [Google Scholar] Pyke C, Heller RS, Kirk RK, Orskov C, Reedtz-Runge S, Kaastrup P, et al

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It also led to a two percent reduction in blood sugar levels compared to the highest dose of semaglutide

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