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This study analysed these data
Among 38 identified hits, we found a subset of chloroacetamides with broad senolytic activity
Other important adverse effects include acute pancreatitis (presenting as severe, persistent abdominal pain radiating to the back), gallbladder disease , and acute kidney injury , particularly in the context of severe gastrointestinal side effects leading to dehydration
SULT2A1 is also termed as dehydroepiandrosterone sulfotransferase (DHEA ST) and conjugates various hydroxysteroids such as DHEA, androgens, bile acids and oestrone (Comer et al., 1993)
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